Neural Crossroads Laboratory

Cue up the beta rhythm

We examined neural oscillations in the dentate gyrus of the hippocampus as animals encountered cues that were associated with positive or negative outcomes. We observed a reliable shift in the rhythmic profile of the dentate gyrus such that decreases in theta (5-10 Hz) amplitude occurred concurrently with increases in beta (15-30 Hz) amplitude. These oscillatory dynamics suggest that the hippocampus is entering a different processing state, with each rhythm operating under different neural mechanisms. We propose that the shift mediates the processing of meaningful cues in the dentate gyrus. Read our publication here.